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The main difference between androgenic and anabolic is that androgenic steroids generate male sex hormone-related activity whereas anabolic steroids increase both muscle mass and the bone mass, respectively. Testosterone is a male sex hormone that acts through a direct antagonism to androgenic receptors via their agonistic (androgenic) and non-antagonistic (androgen-independent) effects on phosphoinositide 3-kinase levels; thus, testosterone has the potential to increase the rate of bone formation through stimulating bone resorption. However, testosterone has little or no effect on bone formation when taken alone or when coupled with other anabolic steroids, finasteride sds.
The major androgenic effects of testosterone are thought to be via the increased expression of the testes-stimulating androgen (TS-α1) and other androgen receptors, keto and corticosteroids. It is post-ulated that androgenic steroids activate the P450 enzyme aromatase or aromatase, which results in increased levels of estradiol and the aromatizable estradiol, Najsilnejsie steroidy na objem. Since post-receptor aromatization is dependent on androgen receptor function, increased estradiol concentration following androgen therapy may stimulate the aromatase activity of T-α1 receptors, which results in the production of the aromatized T-α1 receptor product estrone. This is thought to trigger skeletal hypertrophy.
The testosterone-induced skeletal hypertrophy occurs in several ways; including increased bone mineralization (2, mass fx xtreme anabolic.4%) and protein anabolism (0, mass fx xtreme anabolic.6%), decreased muscle mass (1, mass fx xtreme anabolic.0%), decreased fat mass (0, mass fx xtreme anabolic.3%), and increased circulating testosterone levels (0, mass fx xtreme anabolic.8%), mass fx xtreme anabolic. Additionally, post-treatment with oral administration of testosterone enanthate, an injectable testosterone product that is well tolerated when taken by itself, also increased the muscle mass and strength, as well as skeletal hypertrophy.
There have been numerous clinical trials performed to evaluate androgens for osteoporosis reduction over the past few decades (5, 6). There is very little published data on the use of testosterone for prevention of osteoporosis. Although there are a few studies evaluating the efficacy of testosterone administration for osteoporosis reduction, none of these studies have examined the long-term effects of testosterone supplementation on bone mineral density or spine density in otherwise healthy men, anabolic xtreme mass fx. The effect of testosterone on bone is thought to be related to the direct stimulation of skeletal growth by testosterone and/or its related anabolic steroids and an increase in testosterone.
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